MAIN is a computer program dealing with computational aspects of
macromolecular structure determination used the areas of macromolecular
crystallography and electron microscopy. It is usually run through an
interactive interface. With MAIN a user can
- visualize molecular models and electron density maps using a 3D graphics interface,
- build and rebuilding molecular structures using automated and manual tools,
- modify electron density maps (solvent flattening and flipping, envelopes manipulation, averaging, filtering noise),
- refine structures using real and reciprocal space targets,
- analyze and validate structural models
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